• Culture conditions particularly temperature which

  2020-12-14

  

  Culture conditions (particularly temperature), which affect the pathogenicity of Y. enterocolitica (Bottone, 1997), may also impact its inhibitory properties against cysteine proteases. However, culturing the bacterial strains at 37 instead of 28 °C did not alter remarkably the inhibitory potential

• br Materials and methods br Results The monoclonal antibody

  2020-12-14

  

  Materials and methods Results The monoclonal antibody (mAb), 12G5, reacts specifically with the human fusin protein and recognizes the protein on many T-cell lines such as the SUP-T1 Neochlorogenic acid (Endres et al., 1996). As shown in Fig. 1, AMD3100 at 25 μg/ml completely inhibited the bi

• In solid tumors such as those in breast and

  2020-12-14

  

  In solid tumors, such as those in breast and pancreatic cancer, infiltrating CD68+ or CD163+ tumor-associated macrophages (TAMs) correlate with poor outcome (DeNardo et al., 2011, Kurahara et al., 2011, Shabo et al., 2008). The tumor-promoting function of TAMs is based on their capacity to secrete p

• br Materials and methods br Results

  2020-12-14

  

  Materials and methods Results Discussion This study is the first to our knowledge that describes upstream cis-elements and transcription factors that are important for Crm1 expression and that drive its high expression in cancer and transformed cells. Using deletion and mutation analysis we

• br Materials and methods br

  2020-12-14

  

  Materials and methods Results The i.v. administration of urocortin 2 reduced the mean arterial blood pressure in a dose-dependent manner (Fig. 1). The ED50 for the urocortin 2 cumulative dose–response effect on mean arterial blood pressure was 0.014±0.004 mg kg−1. Urocortin 2 administration ha

• br Methods br Results br Discussion

  2020-12-14

  

  Methods Results Discussion The lowest intra-CeA dose of R278995/CRA0450 that prevented the elevations in meclozine synthesis reward thresholds associated with nicotine withdrawal was 0.05μg/side (0.1μg total bilateral dose). The total bilateral dose in the present study is 100 times lower t

• Previous studies from our laboratory in CD

  2020-12-14

  

  Previous studies from our laboratory in CD1 mice using the incisional postoperative pain model have shown that the incision induces significant mechanical postoperative hyperalgesia lasting between 7 and 10days, with peak effect between 4h-2days (Cabañero et al., 2009a, Cabañero et al., 2009b, Campi

• Previous studies from our laboratory in CD

  2020-12-14

  

  Previous studies from our laboratory in CD1 mice using the incisional postoperative pain model have shown that the incision induces significant mechanical postoperative hyperalgesia lasting between 7 and 10days, with peak effect between 4h-2days (Cabañero et al., 2009a, Cabañero et al., 2009b, Campi

• The CPA EoS was presented by Kontogeorgis et

  2020-12-14

  

  The CPA EoS was presented by Kontogeorgis et al., in 1996 [23]. The proposed equation is composed of two parts (SRK EOS + association term) such that it can well predict the thermodynamic behavior of hydrogen bonding materials as a result of considering the association term. Yakoumis et al. (1997) e

• BMX-IN-1 To evaluate the new quadrupolar CPA qCPA the pure

  2020-12-14

  

  To evaluate the new quadrupolar CPA (qCPA) the pure fluid properties of CO2 are predicted both in the critical region and in the compressed liquid region. The model is furthermore applied for the prediction and correlation of binary mixtures with CO2 and n-alkanes, water, alcohols and a few quadrupo

• Building applications by selecting and integrating

  2020-12-14

  

  Building applications by selecting and integrating components is known in software engineering as COTS-based development. Nowadays, this approach is recognized as a crucial success factor for the software industry (Ahuja, 2014). The advantages of using COTS components include minimizing the overall

• Due to its several industrial

  2020-12-14

  

  Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian Loteprednol etabonate synthesis (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms

• br Acknowledgements br Introduction In Arabidopsis thaliana

  2020-12-14

  

  Acknowledgements Introduction In Arabidopsis thaliana (L.) Heynh, there are at least four copies of the caseine kinase-like gene Ck1, which is involved in peptide phosphorylation in mammals [1]. These genes are distributed on src inhibitors 1, 2, 4, and 5. A similar number of copies for Ck1 ha

• The present study sought to determine if

  2020-12-14

  

  The present study sought to determine if chlorodifluoroacetophenones, such as 3 and 4, were amenable to a radiolabelling methodology to generate potential 18F imaging agents with high cholinesterase affinity. A number of procedures have been reported for the synthesis of trifluoromethyl ketones, inc

• Interestingly increased level of both circulating

  2020-12-14

  

  Interestingly, increased level of both circulating ET-1 and urinary excretion of ET-1 have been observed in patients treated with nephrotoxic immunosuppressive agents as cyclosporine A and tacrolimus (Slowinski et al., 2002). Other nephrotoxic agents, such as cisplatin, also increase urinary excreti

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