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The aim of the present study
2021-07-20

The aim of the present study was to investigate the acute effects of THC on resting state Volasertib neurophysiology, and to examine the impact of COMT genotype on these effects. Thirty-nine healthy volunteers participated in a randomised, placebo-controlled, crossover pharmacological MRI study. Ac
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Introduction Progesterone also known as P is a steroid
2021-07-20

Introduction Progesterone, also known as P4, is a steroid hormone acting as a key component in the complex regulation of female reproductive function. P4 plays major physiological roles in the uterus and ovary by releasing mature oocytes helping in implantation and maintenance of pregnancy, as well
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Material and Methods We reviewed the following databases to
2021-07-20

Material and Methods We reviewed the following databases to obtain relevant studies of udenafil: PubMed, Embase, and the Cochrane Library. The following search terms were used: (“udenafil” OR “Zydena” OR “DA 8159”) AND (“Erectile Dysfunction” OR “Impotence”). We also searched the references of incl
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Recent reports revealed that CSE affects the endothelial cel
2021-07-19

Recent reports revealed that CSE affects the endothelial cells of various tissues like kidney, liver, heart including amprolium synthesis [26,30]. The damage of brain endothelial cells enhances the progress of cognitive dysfunction due to the accumulation of toxic free bio-radicals and activation o
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DGAT is specifically responsible for endogenous synthesis of
2021-07-19

DGAT2 is specifically responsible for endogenous synthesis of TAGs which are then packed into cytosolic LDs in the cytosol for storage and luminal apolipoprotein B (apoB)-containing LDs in the ER lumen destined for VLDL secretion [122,127]. DGAT2 can also synthesize TAG using exogenous FAs and suppo
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Overall the DDR kinase domain
2021-07-19

Overall, the DDR1 kinase domain has a typical kinase domain structure and adequate sequence and/or structure similarity with other kinase domains, as shown in Fig. 2, which allow homology modeling of the active and inactive conformations. In addition to conformational changes to the activation loop
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Keratin K has been identified
2021-07-19

Keratin 8 (K8) has been identified as the first intermediate filament expressed during development in amphibians and mammals. In zebrafish, a type II cytokeratin 8 (zf-K8) cDNA has been cloned. zf-K8 gene was maternally inherited and expressed in all surface cells throughout the embryonic stages old
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br Discussion Our data demonstrate that the bicyclam
2021-07-19

Discussion Our data demonstrate that the bicyclam AMD3100 strongly interacts with CXCR-4, whereas DS and AR177, two other compounds that also interfere with virus entry into the urotensin ii (and interfere with virus binding), do not. AMD3100 is a unique compound in that it interferes with the c
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This review focuses on the
2021-07-19

This review focuses on the atomic basis of CRM1-mediated nuclear export. There are now 27 crystal structures of CRM1 in the Protein Data Bank (PDB) (www.rcsb.org) [64]. Collectively, this large body of work explains various aspects of CRM1 function. Here we summarize the structure–function studies t
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The use of AACSB accreditation as an indicator of
2021-07-19

The use of AACSB accreditation as an indicator of expected performance on the CPA exam has been examined by prior studies (e.g. Barilla et al., 2008, Boone et al., 2006, Grant et al., 2002, Howell and Heshizer, 2006, Lindsay and Campbell, 2003, Marts et al., 1998). While these studies are based on d
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On top of the hardware
2021-07-19

On top of the hardware, ASTS employs Linux SUSE with High-Availability (HA) Extension: a COTS OS provided with two clustering software (Pacemaker Cluster Resource Manager (CRM) and Corosync) responsible for resources orchestration, failure diagnosis, nodes coordination, and fail-over management. The
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The small intestine is the only organ responsible for the
2021-07-19

The small intestine is the only organ responsible for the BCTC of dietary and biliary cholesterol, leaving the unabsorbed cholesterol to be excreted in feces and together contributing to the body cholesterol homeostasis [13], [21], [33], [34]. Following intraluminal hydrolysis, free cholesterol is
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br Experimental br Results br Discussion In the
2021-07-19

Experimental Results Discussion In the last two decades, several studies have shown an important role for progestogens, and in particular ALLO, in the modulation of Schwann cell physiology, regulating several biochemical and functional parameters. The classical PR has been found both in rat
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antibiotics It remains unclear how LINE RNA Nucleolin Kap ar
2021-07-19

It remains unclear how LINE1 RNA-Nucleolin-Kap1 are targeted to the Dux cluster. LINE1-Nucleolin-Kap1 may have other interacting partners with DNA binding specificity. For example, YY1 has been implicated in targeting a repressive complex containing Nucleolin to the human DUX4 cluster (Gabellini et
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Carbonization and decarbonation are two different phases in
2021-07-19

Carbonization and decarbonation are two different phases in the decomposition of rice husk. Silica in RHA melts around 1440°C [5]. Burning of rice husk at temperature lower than 800°C produces reactive amorphous silica which contains approximately 90% silica, whereas above this temperature some crys
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