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br Materials and methods br Results br
2022-01-24
Materials and methods Results Discussion A synoptic review of these cases will be given. In Case 1 the process presented in a photodistributed fashion in a 79-year-old woman; while the infiltrate was atypical, it was non-effacing with polyclonal molecular studies. The disease eventually res
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In vertebrates three cognate receptors or receptor like sequ
2022-01-24
In vertebrates, three cognate receptors or receptor-like sequences have been identified with distinct distributions and functions (Millar, 2005, Neill et al., 2001). Only two types of GnRHR occur in mammals, though (Morgan and Millar, 2004). The mammalian type I GnRHR shares over 80% amino sr1 iden
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Previously localization studies have been
2022-01-21
Previously, localization studies have been conducted using antibody-based detection of Pgp protein in tissues of Clade V nematodes. In transgenic C. elegans, Cel-Pgp-3 and Cel-Pgp-1 proteins localized to the apical membranes of the excretory and intestinal cells and the anterior pharynx (Broeks et a
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Acetylation of histones by histone acetyltransferases
2022-01-21
Acetylation of histones by histone acetyltransferases stimulates gene expression by relaxing arginase inhibitors structure, allowing access of transcription factors to DNA, whereas deacetylation of histones by histone deacetylases promotes chromatin condensation and transcriptional repression. Rece
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Production of reactive oxygen species ROS at the
2022-01-21
Production of reactive oxygen species (ROS) at the site of pathogen attack following recognition of pathogen-associated molecular patterns (PAMPs) is regarded as one of the initial plant immune responses. ROS accumulation can induce a hypersensitive reaction in host plants, thereby causing programme
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Human immunodeficiency virus type HIV is responsible for the
2022-01-21
Human immunodeficiency virus type 1 (HIV-1) is responsible for the si cid pandemic; notification is compulsory in Brazilian blood banks since 1988. From 1980 to 2016, the Brazilian MH reported 882,810 HIV/AIDS cases, with 52.3% in the southeast region. HIV/HCV co-infection has been associated with
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br Conclusion br Disclosure of interest br Acknowledgement b
2022-01-21
Conclusion Disclosure of interest Acknowledgement Introduction Vitamin B6 has long been recognized as a cofactor for many enzymes, especially those involved in amino bafilomycin metabolism. Apart from its role as coenzyme, recent studies are unveiling a new role of vitamin B6 as a chemo
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The observed glucose intolerance and elevated fasting
2022-01-21
The observed glucose intolerance and elevated fasting blood glucose in this study is in consonance with earlier study (Ferris and Kahn, 2012). These have been the common features of GC exposure and are not unexpected. Previous researches that reported IR during GC exposure have shown controversy con
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br Activity dependent control of myelination and myelin
2022-01-20
Activity-dependent control of myelination and myelin maintenance Oligodendrocytes have intrinsic myelinating capacity and can myelinate fixed L-Adrenaline in addition to synthetic nanofibers and micropillars [21, 34, 35]. What prevents oligodendrocytes from myelinating dendrites or other cells i
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Recently we suggested that KYNA an endogenous GPR agonist co
2022-01-20
Recently, we suggested that KYNA – an endogenous GPR35 agonist could be produced in a human cornea since we showed the presence of the enzymes that catalyze the synthesis of KYNA – kynurenine aminotransferases I-III in corneal epithelium, stroma and endothelium (). Therefore, these findings provided
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Neostigmine Bromide A high throughput screening campaign
2022-01-20
A high-throughput screening campaign of the Lilly corporate compound collection led to the discovery of as potent and selective inhibitor of GlyT1 (IC=45nM, GlyT2 IC>30,000nM). In addition to the characteristic -methyl glycine moiety as acidic head group and the novel ethanolamine linker, also co
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Pediatric cancers are fundamentally different from adult tum
2022-01-20
Pediatric cancers are fundamentally different from adult tumors and usually display a lower mutational burden and a faster growth rate. About 30% of all childhood malignancies are solid tumors and, in a majority of cases, respond well to chemotherapy. However, in particular in neuroblastoma the succ
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In this study we demonstrate that the ETS transcription fact
2022-01-20
In this study, we demonstrate that the ETS transcription factor ETV5 is involved in the regulation of ghrelin system in response to the altered nutritional state. In the recent multiple GWAS studies, three single nucleotide polymorphisms (SNPs) of ETV5, rs7647305 (Thorleifsson et al., 2009; Willer e
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We are aware that the classical biochemical view
2022-01-20
We are aware that the classical biochemical view is centered on the local concentrations of specific ion and molecules rather than on cell electric potentials. However, important downstream processes can be influenced by acting locally on these potentials because they regulate the conductance of the
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br Conclusions br Acknowledgments This
2022-01-20
Conclusions Acknowledgments This study was supported by funds from the National Natural Science Foundation of China (NSFC 31360245, 31460258) and the Applied Basic Research Foundation of Yunnan Province of China (2011FZ111). Introduction Acute myocardial infarction is the undoubted cause o
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